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Evaluating the utility of identity-by-descent segment numbers for relatedness inference via information theory and classification

Despite decades of methods development for classifying relatives in genetic studies, pairwise relatedness methods’ recalls are above 90% only for first through third-degree relatives. The top-performing approaches, which leverage identity-by-descent segments, often use only kinship coefficients, whi...

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Detalles Bibliográficos
Autores principales: Smith, Jesse, Qiao, Ying, Williams, Amy L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157175/
https://www.ncbi.nlm.nih.gov/pubmed/35348675
http://dx.doi.org/10.1093/g3journal/jkac072