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Enhanced cobalamin biosynthesis in Ensifer adhaerens by regulation of key genes with gradient promoters

Cobalamin is an essential human vitamin widely used in the pharmaceutical, food, and feed additive industries and currently produced by bacteria or archaea. Ensifer adhaerens HY-1 is an industrial strain that also produces cobalamin. However production outputs are poor and the specific synthesis pat...

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Detalles Bibliográficos
Autores principales: Xu, Sha, Xiao, Zhiqiang, Yu, Shiqin, Zeng, Weizhu, Zhu, Yongming, Zhou, Jingwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157374/
https://www.ncbi.nlm.nih.gov/pubmed/35664931
http://dx.doi.org/10.1016/j.synbio.2022.04.012