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Enhanced cobalamin biosynthesis in Ensifer adhaerens by regulation of key genes with gradient promoters
Cobalamin is an essential human vitamin widely used in the pharmaceutical, food, and feed additive industries and currently produced by bacteria or archaea. Ensifer adhaerens HY-1 is an industrial strain that also produces cobalamin. However production outputs are poor and the specific synthesis pat...
Autores principales: | Xu, Sha, Xiao, Zhiqiang, Yu, Shiqin, Zeng, Weizhu, Zhu, Yongming, Zhou, Jingwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157374/ https://www.ncbi.nlm.nih.gov/pubmed/35664931 http://dx.doi.org/10.1016/j.synbio.2022.04.012 |
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