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Hydrostatic pressure induces profibrotic properties in hepatic stellate cells via the RhoA/ROCK signaling pathway

Elevated interstitial fluid hydrostatic pressure is commonly observed in diseased livers. We herein examined the hypothesis that hydrostatic pressure induces hepatic stellate cells to acquire profibrotic properties under pathological conditions. Human hepatic stellate cells were exposed to 50 mmHg p...

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Detalles Bibliográficos
Autores principales: Huang, Zisheng, Khalifa, Mahmoud Osman, Gu, Weili, Li, Tao‐Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157409/
https://www.ncbi.nlm.nih.gov/pubmed/35357779
http://dx.doi.org/10.1002/2211-5463.13405