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Hepatotoxicity of the Major Anthraquinones Derived From Polygoni Multiflori Radix Based on Bile Acid Homeostasis

Polygoni Multiflori Radix (PMR), the dried root of Polygonum Multiflorum Thunb., has been widely used as traditional Chinese medicines in clinical practice for centuries. However, the frequently reported hepatotoxic adverse effects hindered its safe use in clinical practice. This study aims to explo...

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Detalles Bibliográficos
Autores principales: Kang, Li, Li, Dan, Jiang, Xin, Zhang, Yao, Pan, Minhong, Hu, Yixin, Si, Luqin, Zhang, Yongjun, Huang, Jiangeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157432/
https://www.ncbi.nlm.nih.gov/pubmed/35662717
http://dx.doi.org/10.3389/fphar.2022.878817