Evaluation of human thyroid hormone receptor-antagonist activity in 691 chemical compounds using a yeast two-hybrid assay with Saccharomyces cerevisiae Y190

The human thyroid receptor (hTR)-antagonist activities of 691 compounds were evaluated using a yeast two-hybrid assay with Saccharomyces cerevisiae Y190 introduced hTRα and coactivator. In parallel, those YTOX tests were conducted to evaluate whether those compounds affected either antagonism or tox...

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Detalles Bibliográficos
Autores principales: Omagari, Ryo, Yagishita, Mayuko, Shiraishi, Fujio, Kamata, Ryo, Terasaki, Masanori, Kubo, Takuya, Nakajima, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157443/
https://www.ncbi.nlm.nih.gov/pubmed/35664659
http://dx.doi.org/10.1016/j.dib.2022.108303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157443/
https://www.ncbi.nlm.nih.gov/pubmed/35664659
http://dx.doi.org/10.1016/j.dib.2022.108303

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