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Three-dimensional spheroids of choroid-retinal vascular endothelial cells as an in-vitro model for diabetic retinopathy: Proof-of-concept investigation

Diabetic retinopathy (DR) is a primary microvascular complication of diabetes mellitus and a vision-threatening condition. Vascular endothelial growth factor (VEGF) induces neovascularization and causes metabolic damage to the retinal and choroidal vasculature in diabetic patients. Existing drug scr...

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Detalles Bibliográficos
Autores principales: Gore, Manish, Tiwari, Ankit, Jahagirdar, Devashree, Narayanasamy, Angayarkanni, Jain, Ratnesh, Dandekar, Prajakta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157473/
https://www.ncbi.nlm.nih.gov/pubmed/35663283
http://dx.doi.org/10.1016/j.crphar.2022.100111