Protocol for high-throughput cloning, expression, purification, and evaluation of bispecific antibodies

Bispecific antibodies are a powerful new class of therapeutics, but their development often requires enormous amounts of time and resources. Here, we describe a high-throughput protocol for cloning, expressing, purifying, and evaluating bispecific antibodies. This protocol enables the rapid screenin...

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Detalles Bibliográficos
Autores principales: Li, Danqing, Partin, Alexander C., Zhao, Liangjun, Chen, Irwin, Michaels, Mark L., Wang, Zhulun, Garces, Fernando, Gong, Danyang, Riley, Timothy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157557/
https://www.ncbi.nlm.nih.gov/pubmed/35664258
http://dx.doi.org/10.1016/j.xpro.2022.101428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157557/
https://www.ncbi.nlm.nih.gov/pubmed/35664258
http://dx.doi.org/10.1016/j.xpro.2022.101428

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