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Protocol for high-throughput cloning, expression, purification, and evaluation of bispecific antibodies
Bispecific antibodies are a powerful new class of therapeutics, but their development often requires enormous amounts of time and resources. Here, we describe a high-throughput protocol for cloning, expressing, purifying, and evaluating bispecific antibodies. This protocol enables the rapid screenin...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157557/ https://www.ncbi.nlm.nih.gov/pubmed/35664258 http://dx.doi.org/10.1016/j.xpro.2022.101428 |