Clozapine Long-Term Treatment Might Reduce Epigenetic Age Through Hypomethylation of Longevity Regulatory Pathways Genes

Long-term studies have shown significantly lower mortality rates in patients with continuous clozapine (CLZ) treatment than other antipsychotics. We aimed to evaluate epigenetic age and DNA methylome differences between CLZ-treated patients and those without psychopharmacological treatment. The DNA...

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Detalles Bibliográficos
Autores principales: Pérez-Aldana, Blanca Estela, Martínez-Magaña, José Jaime, Mayén-Lobo, Yerye Gibrán, Dávila-Ortiz de Montellano, David José, Aviña-Cervantes, Carlos Luis, Ortega-Vázquez, Alberto, Genis-Mendoza, Alma Delia, Sarmiento, Emmanuel, Soto-Reyes, Ernesto, Juárez-Rojop, Isela Esther, Tovilla-Zarate, Carlos Alfonso, González-Castro, Thelma Beatriz, Nicolini, Humberto, López-López, Marisol, Monroy-Jaramillo, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157596/
https://www.ncbi.nlm.nih.gov/pubmed/35664466
http://dx.doi.org/10.3389/fpsyt.2022.870656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157596/
https://www.ncbi.nlm.nih.gov/pubmed/35664466
http://dx.doi.org/10.3389/fpsyt.2022.870656

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