A Novel Small-Molecule Inhibitor of SREBP-1 Based on Natural Product Monomers Upregulates the Sensitivity of Lung Squamous Cell Carcinoma Cells to Antitumor Drugs

The transcription factor, sterol regulatory element binding protein 1 (SREBP-1), plays important roles in modulating the proliferation, metastasis, or resistance to antitumor agents by promoting cellular lipid metabolism and related cellular glucose-uptake/Warburg Effect. However, the underlying mec...

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Detalles Bibliográficos
Autores principales: Ma, De-Bin, Liu, Xing-Yu, Jia, Hui, Zhang, Yingshi, Jiang, Qiyu, Sun, Huiwei, Li, Xiaojuan, Sun, Fang, Chai, Yantao, Feng, Fan, Liu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157598/
https://www.ncbi.nlm.nih.gov/pubmed/35662712
http://dx.doi.org/10.3389/fphar.2022.895744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157598/
https://www.ncbi.nlm.nih.gov/pubmed/35662712
http://dx.doi.org/10.3389/fphar.2022.895744

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