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Robust drug bioavailability and safety for rheumatoid arthritis therapy using D-amino acids-based supramolecular hydrogels

Long-term use of disease-modifying anti-rheumatic drugs (DMARDs) such as methotrexate (MTX) shows clinical benefits for rheumatoid arthritis (RA) treatment. However, there are growing concerns over the adverse effects of systemic drug administration. Therefore, a strategy that can enhance drug bioav...

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Detalles Bibliográficos
Autores principales: Ma, Shaodan, Gu, Shunan, Zhang, Jinwei, Qi, Weizhong, Lin, Zhaowei, Zhai, Weicheng, Zhan, Jie, Li, Qi, Cai, Yanbin, Lu, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157599/
https://www.ncbi.nlm.nih.gov/pubmed/35665233
http://dx.doi.org/10.1016/j.mtbio.2022.100296