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Evaluating the regulation of transporter proteins and P-glycoprotein in rats with cholestasis and its implication for digoxin clearance

BACKGROUND: Cardiac and hepatic functionality are intertwined in a multifaceted relationship. Pathologic processes involving one may affect the other through a variety of mechanisms, including hemodynamic and membrane transport effects. AIM: To better understand the effect of extrahepatic cholestasi...

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Detalles Bibliográficos
Autores principales: Giroux, Parker, Kyle, Patrick B, Tan, Chalet, Edwards, Joseph D, Nowicki, Michael J, Liu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157686/
https://www.ncbi.nlm.nih.gov/pubmed/35720166
http://dx.doi.org/10.4291/wjgp.v13.i3.73