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Evaluating the regulation of transporter proteins and P-glycoprotein in rats with cholestasis and its implication for digoxin clearance
BACKGROUND: Cardiac and hepatic functionality are intertwined in a multifaceted relationship. Pathologic processes involving one may affect the other through a variety of mechanisms, including hemodynamic and membrane transport effects. AIM: To better understand the effect of extrahepatic cholestasi...
Autores principales: | Giroux, Parker, Kyle, Patrick B, Tan, Chalet, Edwards, Joseph D, Nowicki, Michael J, Liu, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157686/ https://www.ncbi.nlm.nih.gov/pubmed/35720166 http://dx.doi.org/10.4291/wjgp.v13.i3.73 |
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