Synthesis, Preclinical Evaluation, and a Pilot Clinical PET Imaging Study of (68)Ga-Labeled FAPI Dimer

Cancer-associated fibroblasts (CAFs) are crucial components of the tumor microenvironment. Fibroblast activation protein (FAP) is overexpressed in CAFs. FAP-targeted molecular imaging agents, including the FAP inhibitors (FAPIs) 04 and 46, have shown promising results in tumor diagnosis. However, th...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Liang, Niu, Bo, Fang, Jianyang, Pang, Yizhen, Li, Siyang, Xie, Chengrong, Sun, Long, Zhang, Xianzhong, Guo, Zhide, Lin, Qin, Chen, Haojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2022
Materias:
Basic Science Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157726/
https://www.ncbi.nlm.nih.gov/pubmed/34556528
http://dx.doi.org/10.2967/jnumed.121.263016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157726/
https://www.ncbi.nlm.nih.gov/pubmed/34556528
http://dx.doi.org/10.2967/jnumed.121.263016

Ejemplares similares