Design, Synthesis, and Apoptosis-Promoting Effect Evaluation of Rhopaladins’ Analog 4-Arylidene-5-Oxopyrrolidine Derivatives

Marine alkaloids have novel structures and antitumor activities. Therefore, we synthesized rhopaladins’ analogs from marine alkaloids rhopaladins A-D and modified their structures to synthesize 4-benzylidene-5-pyrrolidone derivatives. Among the compounds, (2E, 4E)-4-(4-chlorobenzylidene)-2-(4-chloro...

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Detalles Bibliográficos
Autores principales: Zhu, Jun, Kong, Ling-Qi, Chen, Qin-Hua, Li, Bin, Wu, Lun, Ran, Feng-Ying, Ke, Li-Na, Zeng, Xiao-Hua, Wang, Hong-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157788/
https://www.ncbi.nlm.nih.gov/pubmed/35665067
http://dx.doi.org/10.3389/fchem.2022.898436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157788/
https://www.ncbi.nlm.nih.gov/pubmed/35665067
http://dx.doi.org/10.3389/fchem.2022.898436

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