How does re-classification of variants of unknown significance (VUS) impact the management of patients at risk for hereditary breast cancer?

BACKGROUND: The popularity of multigene testing increases the probability of identifying variants of uncertain significance (VUS). While accurate variant interpretation enables clinicians to be better informed of the genetic risk of their patients, currently, there is a lack of consensus management...

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Detalles Bibliográficos
Autores principales: Kwong, Ava, Ho, Cecilia Yuen Sze, Shin, Vivian Yvonne, Au, Chun Hang, Chan, Tsun-Leung, Ma, Edmond Shiu Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158111/
https://www.ncbi.nlm.nih.gov/pubmed/35641994
http://dx.doi.org/10.1186/s12920-022-01270-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158111/
https://www.ncbi.nlm.nih.gov/pubmed/35641994
http://dx.doi.org/10.1186/s12920-022-01270-4

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