Open chromatin analysis in Trypanosoma cruzi life forms highlights critical differences in genomic compartments and developmental regulation at tDNA loci

BACKGROUND: Genomic organization and gene expression regulation in trypanosomes are remarkable because protein-coding genes are organized into codirectional gene clusters with unrelated functions. Moreover, there is no dedicated promoter for each gene, resulting in polycistronic gene transcription,...

Descripción completa

Detalles Bibliográficos
Autores principales: Lima, Alex Ranieri Jerônimo, Silva, Herbert Guimarães de Sousa, Poubel, Saloe, Rosón, Juliana Nunes, de Lima, Loyze Paola Oliveira, Costa-Silva, Héllida Marina, Gonçalves, Camila Silva, Galante, Pedro A. F., Holetz, Fabiola, Motta, Maria Cristina Machado M., Silber, Ariel M., Elias, M. Carolina, da Cunha, Julia Pinheiro Chagas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158160/
https://www.ncbi.nlm.nih.gov/pubmed/35650626
http://dx.doi.org/10.1186/s13072-022-00450-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158160/
https://www.ncbi.nlm.nih.gov/pubmed/35650626
http://dx.doi.org/10.1186/s13072-022-00450-x

Ejemplares similares