Open chromatin analysis in Trypanosoma cruzi life forms highlights critical differences in genomic compartments and developmental regulation at tDNA loci

BACKGROUND: Genomic organization and gene expression regulation in trypanosomes are remarkable because protein-coding genes are organized into codirectional gene clusters with unrelated functions. Moreover, there is no dedicated promoter for each gene, resulting in polycistronic gene transcription,...

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Detalles Bibliográficos
Autores principales: Lima, Alex Ranieri Jerônimo, Silva, Herbert Guimarães de Sousa, Poubel, Saloe, Rosón, Juliana Nunes, de Lima, Loyze Paola Oliveira, Costa-Silva, Héllida Marina, Gonçalves, Camila Silva, Galante, Pedro A. F., Holetz, Fabiola, Motta, Maria Cristina Machado M., Silber, Ariel M., Elias, M. Carolina, da Cunha, Julia Pinheiro Chagas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158160/
https://www.ncbi.nlm.nih.gov/pubmed/35650626
http://dx.doi.org/10.1186/s13072-022-00450-x

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