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Nalbuphine alleviates inflammation by down-regulating NF-κB in an acute inflammatory visceral pain rat model
INTRODUCTION: Nalbuphine can relieve patients’ inflammation response after surgery compared to other opioid drugs. However, its molecular mechanism has not been clear. Activation of NF-κB signaling pathway under oxidative stress and inflammation can maintain pain escalation. METHODS: We firstly inve...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158276/ https://www.ncbi.nlm.nih.gov/pubmed/35642022 http://dx.doi.org/10.1186/s40360-022-00573-7 |