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Nalbuphine alleviates inflammation by down-regulating NF-κB in an acute inflammatory visceral pain rat model

INTRODUCTION: Nalbuphine can relieve patients’ inflammation response after surgery compared to other opioid drugs. However, its molecular mechanism has not been clear. Activation of NF-κB signaling pathway under oxidative stress and inflammation can maintain pain escalation. METHODS: We firstly inve...

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Detalles Bibliográficos
Autores principales: Ruan, Dijiao, Wang, Yuanyuan, Li, Sisi, Zhang, Chao, Zheng, Wenwen, Yu, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158276/
https://www.ncbi.nlm.nih.gov/pubmed/35642022
http://dx.doi.org/10.1186/s40360-022-00573-7