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Crystal structure of an extracellular superoxide dismutase from Onchocerca volvulus and implications for parasite-specific drug development

Superoxide dismutases (SODs) are metalloproteins that are responsible for the dismutation of superoxide anion radicals. SODs are consequently protective against oxidative damage to cellular components. Among other protective mechanisms, the filarial parasite Onchocerca volvulus has a well developed...

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Detalles Bibliográficos
Autores principales: Moustafa, Amr, Perbandt, Markus, Liebau, Eva, Betzel, Christian, Falke, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158661/
https://www.ncbi.nlm.nih.gov/pubmed/35647680
http://dx.doi.org/10.1107/S2053230X22005350