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Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men

Preclinical studies have revealed that the elevation of nicotinamide adenine dinucleotide (NAD + ) upon the administration of nicotinamide mononucleotide (NMN), an NAD + precursor, can mitigate aging-related disorders; however, human data on this are limited. We investigated whether the chronic oral...

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Detalles Bibliográficos
Autores principales: Igarashi, Masaki, Nakagawa-Nagahama, Yoshiko, Miura, Masaomi, Kashiwabara, Kosuke, Yaku, Keisuke, Sawada, Mika, Sekine, Rie, Fukamizu, Yuichiro, Sato, Toshiya, Sakurai, Takanobu, Sato, Jiro, Ino, Kenji, Kubota, Naoto, Nakagawa, Takashi, Kadowaki, Takashi, Yamauchi, Toshimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158788/
https://www.ncbi.nlm.nih.gov/pubmed/35927255
http://dx.doi.org/10.1038/s41514-022-00084-z