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A pan-tissue DNA-methylation epigenetic clock based on deep learning

Several age predictors based on DNA methylation, dubbed epigenetic clocks, have been created in recent years, with the vast majority based on regularized linear regression. This study explores the improvement in the performance and interpretation of epigenetic clocks using deep learning. First, we g...

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Detalles Bibliográficos
Autores principales: de Lima Camillo, Lucas Paulo, Lapierre, Louis R., Singh, Ritambhara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9158789/
http://dx.doi.org/10.1038/s41514-022-00085-y