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Astrocyte reactivity in a mouse model of SCN8A epileptic encephalopathy
OBJECTIVE: SCN8A epileptic encephalopathy is caused predominantly by de novo gain‐of‐function mutations in the voltage‐gated sodium channel Na(v)1.6. The disorder is characterized by early onset of seizures and developmental delay. Most patients with SCN8A epileptic encephalopathy are refractory to...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159254/ https://www.ncbi.nlm.nih.gov/pubmed/34826216 http://dx.doi.org/10.1002/epi4.12564 |