Abundance of Noncircular Intrahepatic Hepatitis B Virus DNA May Reflect Frequent Integration Into Human DNA in Chronically Infected Patients

BACKGROUND: Hepatitis B virus (HBV) integration has implications for cancer development and surface antigen (HBsAg) production, but methods to quantify integrations are lacking. The aim of this study was to develop a droplet digital PCR (ddPCR) assay discriminating between circular and integrated HB...

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Detalles Bibliográficos
Autores principales: Rydell, Gustaf E, Larsson, Simon B, Prakash, Kasthuri, Andersson, Maria, Norder, Heléne, Hellstrand, Kristoffer, Norkrans, Gunnar, Lindh, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159317/
https://www.ncbi.nlm.nih.gov/pubmed/32910825
http://dx.doi.org/10.1093/infdis/jiaa572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159317/
https://www.ncbi.nlm.nih.gov/pubmed/32910825
http://dx.doi.org/10.1093/infdis/jiaa572

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