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Predictive Modeling to Study the Treatment-Shortening Potential of Novel Tuberculosis Drug Regimens, Toward Bundling of Preclinical Data

BACKGROUND: Given the persistently high global burden of tuberculosis, effective and shorter treatment options are needed. We explored the relationship between relapse and treatment length as well as interregimen differences for 2 novel antituberculosis drug regimens using a mouse model of tuberculo...

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Detalles Bibliográficos
Autores principales: Mudde, Saskia E, Ayoun Alsoud, Rami, van der Meijden, Aart, Upton, Anna M, Lotlikar, Manisha U, Simonsson, Ulrika S H, Bax, Hannelore I, de Steenwinkel, Jurriaan E M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159334/
https://www.ncbi.nlm.nih.gov/pubmed/33606880
http://dx.doi.org/10.1093/infdis/jiab101