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Critical cysteines in the functional interaction of adenylyl cyclase isoform 6 with Gαs

Activation of adenylyl cyclases (ACs) by G‐protein Gαs catalyzes the production of cyclic adenosine monophosphate (cAMP), a key second messenger that regulates diverse physiological responses. There are 10 AC isoforms present in humans, with AC5 and AC6 proposed to play vital roles in cardiac functi...

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Detalles Bibliográficos
Autores principales: Bhagirath, Anjali Y., Bhatia, Vikram, Medapati, Manoj Reddy, Singh, Nisha, Hinton, Martha, Chelikani, Prashen, Dakshinamurti, Shyamala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159366/
https://www.ncbi.nlm.nih.gov/pubmed/35664968
http://dx.doi.org/10.1096/fba.2021-00073