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α-Synuclein in the Synaptic Vesicle Liquid Phase: Active Player or Passive Bystander?

The protein α-synuclein, which is well-known for its links to Parkinson’s Disease, is associated with synaptic vesicles (SVs) in nerve terminals. Despite intensive studies, its precise physiological function remains elusive. Accumulating evidence indicates that liquid-liquid phase separation takes p...

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Detalles Bibliográficos
Autores principales: Brodin, Lennart, Milovanovic, Dragomir, Rizzoli, Silvio O., Shupliakov, Oleg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159372/
https://www.ncbi.nlm.nih.gov/pubmed/35664678
http://dx.doi.org/10.3389/fmolb.2022.891508