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Butyric Acid Ameliorates Myocardial Fibrosis by Regulating M1/M2 Polarization of Macrophages and Promoting Recovery of Mitochondrial Function

BACKGROUND: We aimed to investigate the effect and mechanism of butyric acid on rat myocardial fibrosis (MF). METHODS: 16S rRNA sequencing was used to analyze the gut microbiota characteristics of the Sham group and MF group. HPLC was applied to measure butyric acid in the feces and serum. In vitro,...

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Detalles Bibliográficos
Autores principales: Li, Xiaogang, Li, Ruixuan, You, Nana, Zhao, Xiexiong, Li, Jiaying, Jiang, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159497/
https://www.ncbi.nlm.nih.gov/pubmed/35662928
http://dx.doi.org/10.3389/fnut.2022.875473