Machine learning predicts translation initiation sites in neurologic diseases with nucleotide repeat expansions

A number of neurologic diseases associated with expanded nucleotide repeats, including an inherited form of amyotrophic lateral sclerosis, have an unconventional form of translation called repeat-associated non-AUG (RAN) translation. It has been speculated that the repeat regions in the RNA fold int...

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Detalles Bibliográficos
Autores principales: Gleason, Alec C., Ghadge, Ghanashyam, Chen, Jin, Sonobe, Yoshifumi, Roos, Raymond P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159584/
https://www.ncbi.nlm.nih.gov/pubmed/35648796
http://dx.doi.org/10.1371/journal.pone.0256411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159584/
https://www.ncbi.nlm.nih.gov/pubmed/35648796
http://dx.doi.org/10.1371/journal.pone.0256411

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