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TFAP2 paralogs facilitate chromatin access for MITF at pigmentation and cell proliferation genes

In developing melanocytes and in melanoma cells, multiple paralogs of the Activating-enhancer-binding Protein 2 family of transcription factors (TFAP2) contribute to expression of genes encoding pigmentation regulators, but their interaction with Microphthalmia transcription factor (MITF), a master...

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Detalles Bibliográficos
Autores principales: Kenny, Colin, Dilshat, Ramile, Seberg, Hannah E., Van Otterloo, Eric, Bonde, Gregory, Helverson, Annika, Franke, Christopher M., Steingrímsson, Eiríkur, Cornell, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159589/
https://www.ncbi.nlm.nih.gov/pubmed/35580127
http://dx.doi.org/10.1371/journal.pgen.1010207