BR2 cell penetrating peptide effectively delivers anti-p21Ras scFv to tumor cells with ganglioside expression for therapy of ras-driven tumor

PURPOSE: Cell membrane penetrating peptide BR2 can bind with ganglioside and introduce foreign drugs into tumor cells. In this study, we employed BR2 to carry the broad-spectrum anti-p21Ras scFv prepared in our laboratory into ganglioside expressing tumor cells for therapy of ras-driven tumors. METH...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Ting, Shi, Yingxian, Pan, Xinyan, Feng, Qiang, Wang, Peng, Song, Shuling, Yang, Lilin, Yang, Julun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159597/
https://www.ncbi.nlm.nih.gov/pubmed/35648774
http://dx.doi.org/10.1371/journal.pone.0269084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159597/
https://www.ncbi.nlm.nih.gov/pubmed/35648774
http://dx.doi.org/10.1371/journal.pone.0269084

Ejemplares similares