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DIRECT-NET: An efficient method to discover cis-regulatory elements and construct regulatory networks from single-cell multiomics data

The emergence of single-cell multiomics data provides unprecedented opportunities to scrutinize the transcriptional regulatory mechanisms controlling cell identity. However, how to use those datasets to dissect the cis-regulatory element (CRE)–to–gene relationships at a single-cell level remains a m...

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Detalles Bibliográficos
Autores principales:	Zhang, Lihua, Zhang, Jing, Nie, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159696/ https://www.ncbi.nlm.nih.gov/pubmed/35648859 http://dx.doi.org/10.1126/sciadv.abl7393

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