Cargando…

Subtype-specific responses of hKv7.4 and hKv7.5 channels to polyunsaturated fatty acids reveal an unconventional modulatory site and mechanism

The K(V)7.4 and K(V)7.5 subtypes of voltage-gated potassium channels play a role in important physiological processes such as sound amplification in the cochlea and adjusting vascular smooth muscle tone. Therefore, the mechanisms that regulate K(V)7.4 and K(V)7.5 channel function are of interest. He...

Descripción completa

Detalles Bibliográficos
Autores principales: Frampton, Damon JA, Choudhury, Koushik, Nikesjö, Johan, Delemotte, Lucie, Liin, Sara I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159753/
https://www.ncbi.nlm.nih.gov/pubmed/35642964
http://dx.doi.org/10.7554/eLife.77672