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Individualized discovery of rare cancer drivers in global network context

Late advances in genome sequencing expanded the space of known cancer driver genes several-fold. However, most of this surge was based on computational analysis of somatic mutation frequencies and/or their impact on the protein function. On the contrary, experimental research necessarily accounted f...

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Detalles Bibliográficos
Autores principales: Petrov, Iurii, Alexeyenko, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159755/
https://www.ncbi.nlm.nih.gov/pubmed/35593700
http://dx.doi.org/10.7554/eLife.74010