Development of Simple and Accurate in Silico Ligand-Based Models for Predicting ABCG2 Inhibition

The ATP binding cassette transporter ABCG2 is a physiologically important drug transporter that has a central role in determining the ADMET (absorption, distribution, metabolism, elimination, and toxicity) profile of therapeutics, and contributes to multidrug resistance. Thus, development of predict...

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Detalles Bibliográficos
Autores principales: Huang, Shuheng, Gao, Yingjie, Zhang, Xuelian, Lu, Ji, Wei, Jun, Mei, Hu, Xing, Juan, Pan, Xianchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159808/
https://www.ncbi.nlm.nih.gov/pubmed/35665065
http://dx.doi.org/10.3389/fchem.2022.863146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159808/
https://www.ncbi.nlm.nih.gov/pubmed/35665065
http://dx.doi.org/10.3389/fchem.2022.863146

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