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Blockade of NLRP3/Caspase-1/IL-1β Regulated Th17/Treg Immune Imbalance and Attenuated the Neutrophilic Airway Inflammation in an Ovalbumin-Induced Murine Model of Asthma

Asthma is a heterogeneous inflammatory disorder of the airways, and multiple studies have addressed the vital role of the nucleotide-binding oligomerization domain-like receptor family pyrin domain containing 3 (NLRP3)/caspase-1/interleukin-1β (IL-1β) pathway in asthma, but its impact on ovalbumin-...

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Detalles Bibliográficos
Autores principales: Chen, Ling, Hou, Weiwei, Liu, Fen, Zhu, Ruochen, Lv, Anping, Quan, Wenqiang, Mao, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159827/
https://www.ncbi.nlm.nih.gov/pubmed/35664352
http://dx.doi.org/10.1155/2022/9444227