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Intestinal Barrier Dysfunction in the Absence of Systemic Inflammation Fails to Exacerbate Motor Dysfunction and Brain Pathology in a Mouse Model of Parkinson's Disease
INTRODUCTION: Parkinson's disease (PD) is the second most common neurodegenerative disease associated with aging. PD patients have systemic and neuroinflammation which is hypothesized to contribute to neurodegeneration. Recent studies highlight the importance of the gut-brain axis in PD pathoge...
Autores principales: | Jackson, Aeja, Engen, Phillip A., Forsyth, Christopher B., Shaikh, Maliha, Naqib, Ankur, Wilber, Sherry, Frausto, Dulce M., Raeisi, Shohreh, Green, Stefan J., Bradaric, Brinda Desai, Persons, Amanda L., Voigt, Robin M., Keshavarzian, Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159909/ https://www.ncbi.nlm.nih.gov/pubmed/35665034 http://dx.doi.org/10.3389/fneur.2022.882628 |
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