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Genome-wide protein–DNA interaction site mapping in bacteria using a double-stranded DNA-specific cytosine deaminase

DNA–protein interactions are central to fundamental cellular processes, yet widely implemented technologies for measuring these interactions on a genome scale in bacteria are laborious and capture only a snapshot of binding events. We devised a facile method for mapping DNA–protein interaction sites...

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Detalles Bibliográficos
Autores principales: Gallagher, Larry A., Velazquez, Elena, Peterson, S. Brook, Charity, James C., Radey, Matthew C., Gebhardt, Michael J., Hsu, FoSheng, Shull, Lauren M., Cutler, Kevin J., Macareno, Keven, de Moraes, Marcos H., Penewit, Kelsi M., Kim, Jennifer, Andrade, Pia A., LaFramboise, Thomas, Salipante, Stephen J., Reniere, Michelle L., de Lorenzo, Victor, Wiggins, Paul A., Dove, Simon L., Mougous, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159945/
https://www.ncbi.nlm.nih.gov/pubmed/35650286
http://dx.doi.org/10.1038/s41564-022-01133-9