The SWI/SNF ATPase BRG1 facilitates multiple pro-tumorigenic gene expression programs in SMARCB1-deficient cancer cells

Malignant rhabdoid tumor (MRT) is driven by the loss of the SNF5 subunit of the SWI/SNF chromatin remodeling complex and then thought to be maintained by residual SWI/SNF (rSWI/SNF) complexes that remain present in the absence of SNF5. rSWI/SNF subunits colocalize extensively on chromatin with the t...

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Detalles Bibliográficos
Autores principales: Moe, Kylie C., Maxwell, Jack N., Wang, Jing, Jones, Cheyenne A., Csaki, Grace T., Florian, Andrea C., Romer, Alexander S., Bryant, Daniel L., Farone, Anthony L., Liu, Qi, Tansey, William P., Weissmiller, April M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160003/
https://www.ncbi.nlm.nih.gov/pubmed/35650187
http://dx.doi.org/10.1038/s41389-022-00406-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160003/
https://www.ncbi.nlm.nih.gov/pubmed/35650187
http://dx.doi.org/10.1038/s41389-022-00406-6

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