Robust derivation of transplantable dopamine neurons from human pluripotent stem cells by timed retinoic acid delivery

Stem cell therapies for Parkinson’s disease (PD) have entered first-in-human clinical trials using a set of technically related methods to produce mesencephalic dopamine (mDA) neurons from human pluripotent stem cells (hPSCs). Here, we outline an approach for high-yield derivation of mDA neurons tha...

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Detalles Bibliográficos
Autores principales: Alekseenko, Zhanna, Dias, José M., Adler, Andrew F., Kozhevnikova, Mariya, van Lunteren, Josina Anna, Nolbrant, Sara, Jeggari, Ashwini, Vasylovska, Svitlana, Yoshitake, Takashi, Kehr, Jan, Carlén, Marie, Alexeyenko, Andrey, Parmar, Malin, Ericson, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160024/
https://www.ncbi.nlm.nih.gov/pubmed/35650213
http://dx.doi.org/10.1038/s41467-022-30777-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160024/
https://www.ncbi.nlm.nih.gov/pubmed/35650213
http://dx.doi.org/10.1038/s41467-022-30777-8

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