Identification of HMGCR as the anticancer target of physapubenolide against melanoma cells by in silico target prediction

Physapubenolide (PB), a withanolide-type compound extracted from the traditional herb Physalis minima L., has been demonstrated to exert remarkable cytotoxicity against cancer cells; however, its molecular mechanisms are still unclear. In this study, we demonstrated that PB inhibited cell proliferat...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Hai-yan, Yu, Pian, Chen, Xi-sha, Wei, Hui, Cao, Shi-jie, Zhang, Meng, Zhang, Yi, Tao, Yong-guang, Cao, Dong-sheng, Qiu, Feng, Cheng, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160031/
https://www.ncbi.nlm.nih.gov/pubmed/34588618
http://dx.doi.org/10.1038/s41401-021-00745-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160031/
https://www.ncbi.nlm.nih.gov/pubmed/34588618
http://dx.doi.org/10.1038/s41401-021-00745-x

Ejemplares similares