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Identification of HMGCR as the anticancer target of physapubenolide against melanoma cells by in silico target prediction
Physapubenolide (PB), a withanolide-type compound extracted from the traditional herb Physalis minima L., has been demonstrated to exert remarkable cytotoxicity against cancer cells; however, its molecular mechanisms are still unclear. In this study, we demonstrated that PB inhibited cell proliferat...
Autores principales: | Wang, Hai-yan, Yu, Pian, Chen, Xi-sha, Wei, Hui, Cao, Shi-jie, Zhang, Meng, Zhang, Yi, Tao, Yong-guang, Cao, Dong-sheng, Qiu, Feng, Cheng, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160031/ https://www.ncbi.nlm.nih.gov/pubmed/34588618 http://dx.doi.org/10.1038/s41401-021-00745-x |
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