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Role of Tissue Hydraulic Permeability in Convection-Enhanced Delivery of Nanoparticle-Encapsulated Chemotherapy Drugs to Brain Tumour

PURPOSE: Tissue hydraulic permeability of brain tumours can vary considerably depending on the tissue microstructure, compositions in interstitium and tumour cells. Its effects on drug transport and accumulation remain poorly understood. METHODS: Mathematical modelling is applied to predict the drug...

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Detalles Bibliográficos
Autores principales: Yang, Yi, Zhan, Wenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160122/
https://www.ncbi.nlm.nih.gov/pubmed/35474156
http://dx.doi.org/10.1007/s11095-022-03261-7