Combination of co-crystal and nanocrystal techniques to improve the solubility and dissolution rate of poorly soluble drugs

PURPOSE: Solubility and dissolution rate are essential for the oral absorption and bioavailability of poorly soluble drugs. The aim of this study was to prepare nano-co-crystals by combination of nanocrystal and co-crystal technologies, and investigate its effect, in situ, on increased kinetic solub...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Zun, Staufenbiel, Sven, Bodmeier, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160134/
https://www.ncbi.nlm.nih.gov/pubmed/35552985
http://dx.doi.org/10.1007/s11095-022-03243-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160134/
https://www.ncbi.nlm.nih.gov/pubmed/35552985
http://dx.doi.org/10.1007/s11095-022-03243-9

Ejemplares similares