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Combination of co-crystal and nanocrystal techniques to improve the solubility and dissolution rate of poorly soluble drugs
PURPOSE: Solubility and dissolution rate are essential for the oral absorption and bioavailability of poorly soluble drugs. The aim of this study was to prepare nano-co-crystals by combination of nanocrystal and co-crystal technologies, and investigate its effect, in situ, on increased kinetic solub...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160134/ https://www.ncbi.nlm.nih.gov/pubmed/35552985 http://dx.doi.org/10.1007/s11095-022-03243-9 |