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Targeting Glutamine Metabolism Ameliorates Autoimmune Hepatitis via Inhibiting T Cell Activation and Differentiation

BACKGROUND: Autoimmune hepatitis (AIH) is mediated by a cascade of T cell-mediated events directed at liver cells and persistent inflammation within the liver can eventually result in liver cirrhosis. Targeting glutamine metabolism has an impact on T cell activation and differentiation. However, the...

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Detalles Bibliográficos
Autores principales: Yu, Qiang, Tu, Honghu, Yin, Xueyi, Peng, Chang, Dou, Chuanyun, Yang, Wenhua, Wu, Wenbiao, Guan, Xiaotong, Li, Jia, Yan, Hexin, Zang, Yi, Jiang, Haowen, Xia, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160195/
https://www.ncbi.nlm.nih.gov/pubmed/35663990
http://dx.doi.org/10.3389/fimmu.2022.880262