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The Combination of a Novel GLUT1 Inhibitor and Cisplatin Synergistically Inhibits Breast Cancer Cell Growth By Enhancing the DNA Damaging Effect and Modulating the Akt/mTOR and MAPK Signaling Pathways

Breast cancer is the most prevalent cancer and the second leading cause of cancer death in women. Cisplatin is a commonly used chemotherapeutic drug for breast cancer treatment. Owing to serious side effects, the combination of cisplatin with other drugs is an effective strategy to simultaneously re...

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Detalles Bibliográficos
Autores principales: Weng, Hao-Cheng, Sung, Chieh-Ju, Hsu, Jui-Ling, Leu, Wohn-Jenn, Guh, Jih-Hwa, Kung, Fan-Lu, Hsu, Lih-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160228/
https://www.ncbi.nlm.nih.gov/pubmed/35662690
http://dx.doi.org/10.3389/fphar.2022.879748