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Analysis of Mutational Profile of Hypopharyngeal and Laryngeal Head and Neck Squamous Cell Carcinomas Identifies KMT2C as a Potential Tumor Suppressor

Hypopharyngeal cancer is a poorly characterized type of head and neck squamous cell carcinoma (HNSCC) with bleak prognosis and only few studies focusing specifically on the genomic profile of this type of cancer. We performed molecular profiling of 48 HPV (Human Papilloma Virus)-negative tumor sampl...

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Detalles Bibliográficos
Autores principales: Machnicki, Marcin M., Rzepakowska, Anna, Janowska, Joanna I., Pepek, Monika, Krop, Alicja, Pruszczyk, Katarzyna, Stawinski, Piotr, Rydzanicz, Malgorzata, Grzybowski, Jakub, Gornicka, Barbara, Wnuk, Maciej, Ploski, Rafal, Osuch-Wojcikiewicz, Ewa, Stoklosa, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160230/
https://www.ncbi.nlm.nih.gov/pubmed/35664801
http://dx.doi.org/10.3389/fonc.2022.768954