Mycobacterium tuberculosis-Induced Upregulation of the COX-2/mPGES-1 Pathway in Human Macrophages Is Abrogated by Sulfasalazine

Macrophages are the primary human host cells of intracellular Mycobacterium tuberculosis (M.tb) infection, where the magnitude of inflammatory reactions is crucial for determining the outcome of infection. Previously, we showed that the anti-inflammatory drug sulfasalazine (SASP) significantly reduc...

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Detalles Bibliográficos
Autores principales: Wang, Wenfei, Ning, Yuping, Wang, Yejun, Deng, Guofang, Pace, Simona, Barth, Stefanie A., Menge, Christian, Zhang, Kehong, Dai, Youchao, Cai, Yi, Chen, Xinchun, Werz, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160237/
https://www.ncbi.nlm.nih.gov/pubmed/35663935
http://dx.doi.org/10.3389/fimmu.2022.849583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160237/
https://www.ncbi.nlm.nih.gov/pubmed/35663935
http://dx.doi.org/10.3389/fimmu.2022.849583

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